The following articles highlight the development of the hydrogel technology and its use in diagnosis blood borne disease.

Taylor et al. "A lab-on-chip for malaria diagnosis and surveillance." Malaria Journal 13:179 (2014).

Manage D.P., Lauzon J. Atrazhev A., Pang X., Pilarski L.M. "A novel method for sample delivery and testing of whole blood: gel strip PCR for point of care (POC) molecular diagnostics." Lab Chip 13: 4011-4014 (2013).

Manage D.P., Lauzon J. Atrazhev A., Chavali R., Samuel R.A., Morrissey Y.C., Gordy W., Edwards A.L., Larison K., Yanow S.K., Acker J.P., Zahariadis G., Pilarski L.M. "An enclosed in-gel PCR amplification cassette with multi-target, multi-sample detection for platform molecular diagnostics." Lab Chip 13: 2576-2584 (2013). 

Manage D.P., Lauzon J., Atrazhev A., Morrissey Y.C., Edwards A.L., Stickel A.J., Crabtree H.J., Pabbaraju K., Zahariadis G., Yanow S.K., Pilarski L.M. "A miniaturized and integrated gel post platform for multiparameter PCR detection of herpes simplex viruses from raw genital swabs." Lab on a Chip 12 (9): 1664-1671 (2012).

Manage D.P., Morrissey, Y.C., Stickel, A.J., Lauzon, J., Atrazhev, A., Acker, J.P., Pilarski, L.M., "On-Chip PCR amplification of genomic and viral templates in unprocessed whole blood." Microfluidics and Nanofluidics 10 (3): 697-702 (2011).

Atrazhev, A., Manage, D.P., Stickel, A.J., Crabtree, J.H., Pilarski, L.M., and Acker, J.P. "Hydrogel amplification technology for genotyping and pathogen detection." Analytical Chemistry 82 (19): 8079-8087 (2010).




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